Stereotaxic Radiotherapy and Radiosurgery in Treatment of Neurosurgical Cases

Golanov ., Konovalov ., Kornienko V., Kotelnikova ., Gorlachev G., Pronin I., Maryashev S., Arutyunov N.,
Zolotova S., Andronov ., Strukalev V., Soboleva ., Trunin Yu., Ilyalov S., Kostyuchenko V.

Burdenko Research Institute of Neurosurgery, Moscow, Russia


Today different methods of stereotaxic irradiation occupy a more and more important place in treatment of cases with CNS pathology (tumors of various etiology, arteriovenous malformations, functional diseases). Modern methods imply use of special precision devices for radiation therapy and radiosurgery, stereotaxic apparatus and navigation means, powerful software for planning and verifying irradiation with constant control over treatment quality.

A department of radiotherapy and radiosurgery was opened at the Research Institute of Neurosurgery in March of 2005. It is equipped with the Teragam gamma-therapeutic device for conventional radiotherapy, the Primus linear accelerator with different energy of irradiation and the 6-Mev linear accelerator with the Novalis collimator. Besides, there is the Leksell Gamma-Knife apparatus for radiosurgery. We treated 503 cases; 10% of them were children. The majority of cases (45%) had skull base tumors (meningiomas, neurinomas, pituitary adenomas, craniopharyngiomas, chordomas). There were patients with metastatic lesions of the brain (20%), glial neoplasms of different localization (21%), arteriovenous malformations (10%), other tumors and functional diseases (4%). Stereotaxic radiotherapy and radiosurgery were used in 243 and 260 cases respectively. A choice of a method was dependent on a size, localization and histological structure of neoplasm.

The first results proved high efficacy of stereotaxic irradiation both as an independent method and a modality, included into complex or combined treatment of different types of neurosurgical pathology.