(Neurosurgical Department of the Moscow Regional Research Clinical Institute named after Vladimirsky M.F., Moscow, Russia)
A biocomposite implant is a temporary framework, which dissolves with bone formation and allows it to restore its biological integrity. Crystallization of bone apatite on the surface of collagen fibers and between them and formation of mature bone trabeculae are watched on the third-fourth day after implantation. Bone tissue regeneration comes to an end in 12 months.
Defects of the skull were closed in 71 patients. Their average age was 27 years. There were 52 males and 19 females. All the patients were divided into two groups, depending on a material, used for plasty. These groups were comparable from the point of view of main and prognostic signs. The first group, where the above biocomposite material was used, consisted of 31 patients. There were 35 patients in the second "protacryl" group. According to localization, all defects were divided into convexital (44 cases) and parabasal-basal (27 cases). Convexital and parabasal-basal defects were closed in 22 and 14 patients of the first group and 22 and 13 cases of the second group respectively.
An implant effect on dura mater was estimated by comparison of biochemical indices of liquor (proteins and chlorides). Dependence of protein and chloride changes on localization of the skull defect and used material was proved.
Implant rejection was watched in 1 patient (2.7%) of the first group and 5 cases (14.2%) of the second group. It was caused by pyo-septic complications.